Research Paper Volume 12, Issue 10 pp 9781—9792

LncRNA DSCAM-AS1 promotes colorectal cancer progression by acting as a molecular sponge of miR-384 to modulate AKT3 expression

Figure 1. DSCAM-AS1 was upregulated and correlated with poor prognosis in patients with CRC. (A) qRT-PCR shows the lncRNA DSCAM-AS1 expression level in 56 pairs CRC tissues and non-tumor tissues. (B) qRT-PCR shows the lncRNA DSCAM-AS1 expression level in a normal human colon epithelial cell line NCM460 and four human CRC cell lines (LOVO, PKO, SW480 and HT29).(C) 56 patients with CRC were divided into two groups based on a median DSCAM-AS1 value and the association of DSCAM-AS1 expression with overall survival was analyzed with a Kaplan–Meier plot. P < 0.05, **P < 0.01.