Research Paper Volume 12, Issue 13 pp 12812—12840

PHLPP2 is regulated by competing endogenous RNA network in pathogenesis of colon cancer

Figure 7. Overexpressed LINC00402, LINC00461, and SFTA1P inhibit the proliferation and promote apoptosis of HT-29 cells. (A) Fluorescence image by EdU labeling (200 ×) evaluated cell proliferation when HT-29 cells were transfected with overexpressed LINC00402. (B) Fluorescence image by flow cytometry (200 ×) measured cell apoptosis when HT-29 cells were transfected with overexpressed LINC00402. (C) Fluorescence image by EdU labeling (200 ×) evaluated cell proliferation when HT-29 cells were transfected with overexpressed LINC00461. (D) Fluorescence image by flow cytometry (200 ×) assessed cell apoptosis when HT-29 cells were transfected with overexpressed LINC00461. (E) Fluorescence image by EdU labeling (200 ×) cell proliferation evaluated when HT-29 cells were transfected with overexpressed SFTA1P. (F) Fluorescence image by flow cytometry (200 ×) assessed cell apoptosis when HT-29 cells were transfected with overexpressed SFTA1P. * p < 0.05 vs. the NC-pcDNA group; # p < 0.05 vs. the NC-sh group; & p < 0.05 vs. the PHLPP2 group. Measurement data (proliferation rate and apoptosis rate) in this Figure were expressed as the mean ± standard deviation, and comparisons among multiple groups were conducted using One-Way ANOVA; the experiment was repeated three times independently.