Research Paper Volume 12, Issue 13 pp 13076—13089

CircFOXO3 rs12196996, a polymorphism at the gene flanking intron, is associated with circFOXO3 levels and the risk of coronary artery disease

Figure 2. Association between rs12196996 and the expression levels of circFOXO3 or linear FOXO3 in PBMCs in the sum of CAD patients and control subjects. Analysis of circFOXO3 expression levels in PBMCs of individuals carrying AA vs. AG vs. GG genotypes (A) or the combined AA+AG genotypes vs. GG genotype (B). Analysis of linear FOXO3 expression levels in PBMCs of individuals carrying AA vs. AG vs. GG genotypes (C) or the combined AA+AG genotypes vs. GG genotype (D).