Research Paper Volume 12, Issue 13 pp 13488—13501

TRIM29 mediates lung squamous cell carcinoma cell metastasis by regulating autophagic degradation of E-cadherin

Figure 1. TRIM29 gene is highly expressed in lung squamous cell carcinoma tissues. (A) Immunohistochemical analysis of normal tissues and lung squamous cell carcinoma tissues. (B) Western blot analysis of normal tissues and lung squamous cell carcinoma tissues. N: normal tissues; T: tumor tissues. GAPDH was employed as an internal reference. (C) qRT-PCR analysis the TRIM29 mRNA abundance in 30 lung squamous cell carcinoma tissues and paired normal tissues. (D) mRNA abundance analysis of TRIM29 gene in GEPIA database (http://gepia.cancer-pku.cn/index.html). (E) Validate the relationship between the expression of TRIM29 in lung squamous cell carcinoma and survival in Kaplan-Meier Plotter database (http://www.kmplot.com/). *P<0.05.