Research Paper Volume 12, Issue 17 pp 16867—16886

Oxidative stress, apoptosis and inflammatory responses involved in copper-induced pulmonary toxicity in mice

Figure 3. Changes of factors related to ROS production in the lung. (A). 8-OHdG and MDA contents levels in the lung at 21 and 42 days of the experiment. (B) ASA and AHR activities in the lung at 21 and 42 days of the experiment. (C) NO contents, iNOS activities, and mRNA expression in the lung at 21 and 42 days of the experiment. Data are presented with the mean± standard deviation (n=8). *p < 0.05, compared with the control group; **p < 0.01, compared with the control group.