Research Paper Volume 12, Issue 17 pp 16867—16886

Oxidative stress, apoptosis and inflammatory responses involved in copper-induced pulmonary toxicity in mice

Figure 6. Changes of protein and mRNA expression levels of apoptotic related mediators in the lung at 21 and 42 days of the experiment. (A) Western blot assay of apoptosis-related mediators at 21 days. (B) Western blot assay of apoptosis-related mediators at 42 days. (C) The relative protein expression levels of apoptosis-related mediators. (D) The relative mRNA expression levels of apoptosis-related mediators. Data are presented with the mean± standard deviation (n=8). *p < 0.05, compared with the control group; **p < 0.01, compared with the control group.