Research Paper Volume 12, Issue 17 pp 16867—16886

Oxidative stress, apoptosis and inflammatory responses involved in copper-induced pulmonary toxicity in mice

class="figure-viewer-img"

Figure 6. Changes of protein and mRNA expression levels of apoptotic related mediators in the lung at 21 and 42 days of the experiment. (A) Western blot assay of apoptosis-related mediators at 21 days. (B) Western blot assay of apoptosis-related mediators at 42 days. (C) The relative protein expression levels of apoptosis-related mediators. (D) The relative mRNA expression levels of apoptosis-related mediators. Data are presented with the mean± standard deviation (n=8). *p < 0.05, compared with the control group; **p < 0.01, compared with the control group.