Research Paper Volume 12, Issue 22 pp 22527—22537

Cationic solid lipid nanoparticles loaded by integrin β1 plasmid DNA attenuates IL-1β-induced apoptosis of chondrocyte

Figure 4. Solid lipid nanoparticles-integrin β1 overexpression plasmid (SLNs-pDNA) promoted cell proliferation in IL-1β-induced rat chondrocytes. (A) Cell viability of rat chondrocytes treated with IL-1β (model group), or IL-1β + SLNs-pDNA (SLNs-pDNA group) using CCK-8 assay. (B) The percentage of BrdU-positive cells in rat chondrocytes treated with IL-1β (model group), or IL-1β + SLNs-pDNA (SLNs-pDNA group) using BrdU assay. *P < 0.05