Research Paper Volume 12, Issue 19 pp 19022—19044

Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease

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Summary of CNV region and correlation between CNV pattern and gene expression. (A) Circos plot illustrating CNV regions for RNA modification regulators (RNA-MRs). Outermost circle: chromosomes; inner circle: the main type and location of CNVs (red: gain, blue: deletion). (B) Correlation between CNV patterns and expression levels. Ordinal: the relative gene expression levels; abscissa: CNV types. * P < 0.05, ** P < 0.01, and *** P < 0.001 among different CNV types.