Research Paper Volume 12, Issue 20 pp 20285—20307
LncRNA DGCR5 plays a tumor-suppressive role in glioma via the miR-21/Smad7 and miR-23a/PTEN axes
Figure 1. Selection of lncRNAs related to glioma overall survival (A) A schematic diagram showing the process of lncRNA selection. (B) Based on TCGA GBMLGG dataset, we selected 144 lncRNAs that are correlated with better overall survival in glioma patients when they are highly expressed. (C) Based on REMBRANDT dataset, 32 of the 144 lncRNAs are correlated with better overall survival in glioma patients when they are highly expressed. (D) Based on online microarray expression profile (GSE4271), higher lncRNA DGCR5 expression is significantly correlated with better overall survival in glioma patients. (E) Based on TCGA Brain Lower Grade Glioma (LGG) dataset, higher lncRNA DGCR5 expression is significantly correlated with better overall survival in glioma patients.