Correlation of TRIM28 expression with immune cell infiltration. (A) TRIM28 levels were significantly negatively associated with the levels of most tumor-infiltrating lymphocytes across human tumors in the TISIDB database. (B) TRIM28 levels correlated negatively with the levels of central memory CD8+ T cells, myeloid-derived suppressor cells, natural killer T cells, macrophages, neutrophils and regulatory T cells. (C) TRIM28 levels correlated negatively with the infiltrating levels of B cells, CD8+ T cells, macrophages, neutrophils and dendritic cells in LUAD in the TIMER database. LUAD, lung adenocarcinoma; Tcm_CD8, Central memory CD8 T cell; MDSC, Myeloid-derived suppressor cell; NKT, Natural killer T cell; Treg, regulatory T cell. TILs, tumor-infiltrating lymphocytes.