Research Paper Volume 12, Issue 21 pp 21253—21272

Regulation of the regenerative activity of dental pulp stem cells from exfoliated deciduous teeth (SHED) of children by TGF-β1 is associated with ALK5/Smad2, TAK1, p38 and MEK/ERK signaling

Figure 5. Effect of TGF-β1 on COX-2 protein expression of cultured SHED. (A) COX-2 protein expression of SHED after exposure to TGF-β1 for 24 hours. (B) Effect of SB431542 on the TGF-β1-induced COX-2 expression of SHED. (C) Effect of 5z-7oxozeaenol on the TGF-β1-induced COX-2 expression of SHED. (D) Effect of U0126 on the TGF-β1-induced COX-2 expression of SHED. (E) Effect of SB203580 on the TGF-β1-induced COX-2 expression of SHED. One representative western blot picture was shown.