Research Paper Volume 12, Issue 21 pp 21290—21307

S-adenosylmethionine administration inhibits levodopa-induced vascular endothelial growth factor-A expression

Figure 5. The functions of L-dopa and SAM are dependent on the ERK activation. (AE) Primary HUVECs were treated by different concentrations of L-dopa and SAM and 10 μM FR180204 for 24 h. Then, the protein expression levels were analyzed by western blot with the indicated antibodies. α-Tubulin used as an internal normalization control.