Research Paper Volume 12, Issue 21 pp 21290—21307

S-adenosylmethionine administration inhibits levodopa-induced vascular endothelial growth factor-A expression

Figure 7. Docking poses and activity pocket for SAM in the crystal structure of VEGFA (PBD ID: 1MKK). (A) The disulfide bridges between C61A-C104A of VEGFA. (B) Docking site of VEGFA crystal structure. (C and D) Important residues are labeled and shown as sticks to facilitate the localization of PFA or SAM on the active site region in VEGFA.