Research Paper Volume 12, Issue 21 pp 21376—21390

The mechanism of submandibular gland dysfunction after menopause may be associated with the ferroptosis

Figure 4. Lipid peroxidation. (A–C) GPX activity (A), GSH level (B) and GSSH level (C) in the CON and OVX groups. (D) MDA concentration in the serum in the CON and OVX groups. (E) MDA concentration in the submandibular gland tissue in the CON and OVX groups. (F) MDA and HAE concentration in the submandibular gland tissue in the CON and OVX groups. Two-way ANOVA test. *p<0.05, **p<0.01 and ***p<0.001. CON = control, OVX = ovariectomy, GPX = Glutathione peroxidase, GSH = glutathione, GSSG = oxidized GSH, MDA = malondialdehyde, HAE = hydroxyalkenals