Figure 8. PPI network and KEGG pathway analysis for the differentially expressed MAM proteins in PSD and PDZ rats. Intricate PPI networks among the differential proteins in the PSD:ZDF (A) and PDZ:PSD (B) groups. Balls represent proteins, some of which are increased (red balls), others decreased (green balls). KEGG pathway enrichment analysis for differential proteins in the PSD:ZDF (C) and PDZ:PSD (D) rats. Alzheimer's disease pathway map in PSD:ZDF (E) and PDZ:PSD (F) rats, respectively. Oxidative phosphorylation pathway map in PSD:ZDF (G) and PDZ:PSD (H) rats, respectively. The upregulated and downregulated proteins are labeled in pink and green, respectively.