Research Paper Volume 12, Issue 19 pp 19493—19519
Accelerated age-related decline in hippocampal neurogenesis in mice with noise-induced hearing loss is associated with hippocampal microglial degeneration
The impact of NIHL and age on the morphology of microglia in auditory brain regions. Quantification of the impact of NIHL on each individual parameter of microglia in the VCN, DCN, IC, and AC by post hoc pairwise comparisons between groups as a function of age. The values are presented as the mean ± SEM of 6-8 mice per group. *P<0.05, **P<0.01 and ***P<0.001 in post hoc comparisons between age-matched groups after two-way analysis of variance (ANOVA), showing a significant effect of NIHL.