Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 2 pp 1872—1882
Multiwalled carbon nanotubes co-delivering sorafenib and epidermal growth factor receptor siRNA enhanced tumor-suppressing effect on liver cancer
Figure 4. MWNT/Sor/siRNA inhibited growth of HepG2 cells. (A) The protein expression of epidermal growth factor receptor (EGFR) in HepG2 cells treated with PBS (control), MWNTs, siRNA, Sor, MWNT/Sor, or MWNT/Sor/siRNA by western blotting. (B) Colony number of HepG2 cells in control group, MWNTs, siRNA, Sor, MWNT/Sor, or MWNT/Sor/siRNA detected by colony formation assay. (C) Cell apoptosis rate of HepG2 cells in control group, MWNTs, siRNA, Sor, MWNT/Sor, or MWNT/Sor/siRNA tested by flow cytometry assay. (D) The proteins expression including Bax, Bid, Bim, cleaved caspase-3, and cleaved caspase-9, in HepG2 cells in control group, MWNTs, siRNA, Sor, MWNT/Sor, or MWNT/Sor/siRNA measured by western blot. *P < 0.05.