Research Paper Volume 12, Issue 19 pp 19563—19584

Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome

Figure 5. Effects of FWP on c-Fos, GluR1 and GluR2/3 expression in hippocampus CA1, CA3 and DG, and amygdala BLA, in depressive rats with liver-depression and spleen-deficiency syndrome (×400, scale bar = 200 μm). (A, B) The positive expression and positive cell of c-Fos; (C, D) The positive expression and positive cell of GluR1; (E, F) The positive expression and positive cell of GluR2/3. Results are presented as mean ± SD from 25 sections. *P<0.05, **P<0.01 compared with the normal group; #P<0.05, ##P<0.01compared with the model group; P<0.05, ♦♦P<0.01 compared with the sham-operated group.