Research Paper Volume 12, Issue 21 pp 21518—21543

Oncostatin M expression and TP53 mutation status regulate tumor-infiltration of immune cells and survival outcomes in cholangiocarcinoma

Figure 3. Landscapes of Immune Cell Infiltration between CCA and Precancerous Tissues, and between Proliferation and Inflammation Types of CCA. (A) 22 types of immune infiltrating cells in RNA high-through sequencing data between CCA and precancerous tissues; (B) Four types of immune infiltrating cells which are significant different between CCA and precancerous tissues; (C) Overall survival of four types of immune infiltrating cells which are significant different in CCA; (D) 22 types of immune infiltrating cells in GSE32225 data between proliferation and inflammation groups; (E) Stacked bar chart shows proportion of 22 immune infiltrating cells in each sample; (F) PCA (Principal components analysis) based on the content of 22 types of immune infiltrating cells indicated that inflammation and proliferation groups of CCA were generally distributed in two different directions in inflammation group and proliferation group respectively.