Research Paper Advance Articles pp 23739—23760

Red light exaggerated sepsis-induced learning impairments and anxiety-like behaviors

Figure 4. Altered gut bacterial composition at the phylum and order levels. (A) Relative abundance at the phylum level in the different groups. (B) Red light exposure reduced the abundance of Firmicutes in both non-septic and septic mice on day 3 relative to ambient white light or green light exposure. (C) Relative abundance at the order level in the different groups. (D) Red light exposure increased the abundance of Bacteroidales in non-LPS-treated mice on day 3 relative to ambient white light or green light exposure. (E) Red light exposure reduced the abundance of Clostridiales in non-septic mice on day 3 relative to ambient white light or green light exposure, as well as in septic mice on day 3 relative to green light exposure. (F) Red light exposure reduced the abundance of Lactobacillales in non-LPS-treated mice on day 3 relative to ambient white light exposure. Data are presented as the mean ± SEM (n = 6-7/group). **P < 0.01, ***P < 0.001, #P < 0.05, ##P < 0.01.