Figure 2. Establishment and validation of the eight-lncRNA prognostic signature. (A–C) The procedure of establishing the prognostic signature. (D) Correlation between the prognostic signature and the overall survival of patients in the TCGA cohort. The distribution of signature scores (top), survival time (middle) and lncRNA expression levels (bottom). The black dotted lines represent the median signature score cut-off dividing patients into the low- and high-signature groups. The red dots and lines represent the patients in the high-score group. The green dots and lines represent the patients in the low-score group. (E) Kaplan-Meier curves of OS based on the 8-lncRNA signature. (F) ROC curve analyses based on the 8-lncRNA signature.