Research Paper Volume 12, Issue 21 pp 22046—22058

miR-205 inhibits the development of hypertrophic scars by targeting THBS1

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Figure 5.

miR-205 arrests hypertrophic scars in hypertrophic scar mice models. (A) The representative images of the HE examination of hypertrophic scars are shown. (B) The representative images of the Masson assay examination of hypertrophic scars are shown. (C, D) THBS1, TGF-β1, α-SMA, Col1, and Cleavage Caspase 3 expression was accessed by Western blot and real-time PCR, **P < 0.05, vs. control. ##P < 0.05, vs. miR-205+vector.