Research Paper Volume 12, Issue 22 pp 23217—23232

Alteration of tumor-associated macrophage subtypes mediated by KRT6A in pancreatic ductal adenocarcinoma

Figure 6. The ratio of immune cells and gene expression and pathway patterns as a consequence of M0 macrophage numbers in PDAC. (A) Numbers of immune cells in the M0-high group and M0-low group in PDAC according to TCGA data. ***: p<0.001, ****: p<0.0001. (B) Heatmap of the gene expression patterns of the M0-high group and the M0-low group in PDAC. (C) GO (upper) and KEGG (lower) pathway enrichment analyses of DEGs between the M0-high group and the M0-low group. (D) GSEA between the M0-high group and the M0-low group.