Research Paper Advance Articles pp 24184—24207

Construction of circRNA-based ceRNA network to reveal the role of circRNAs in the progression and prognosis of metastatic clear cell renal cell carcinoma

Figure 2. Screening of differentially expressed circRNAs. (A) The differential expression of circRNAs in ccRCC tissue samples compared with normal healthy kidney samples. (B) The differential expression of circRNAs in metastatic ccRCC tissue samples compared with local ccRCC tissue samples. (C) 114 circRNAs related to ccRCC progression and metastasis after the intersection. (D) Heatmap for top 5 up-regulated and top 5 down-regulated differentially expressed circRNAs. ccRCC: clear cell renal cell carcinoma.