Research Paper Advance Articles pp 24255—24269

Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines

Figure 2. Identification of differentially expressed genes (DEGs) in sorafenib resistance. (A) DEGs in sorafenib resistance. (B) Expression of sorafenib-targeted genes in sorafenib-sensitive and -resistant HepG2 cells. (C) Expression of sorafenib-targeted genes in sorafenib-sensitive and -resistant Huh7 cells. (D) Cluster heatmap of DEGs between sorafenib-sensitive and -resistant HepG2 cells. (E) Cluster heatmap between sorafenib-sensitive and -resistant Huh7 cells.