Research Paper Volume 12, Issue 21 pp 22266—22290

Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro

Figure 8. AFM tapping mode images of naked mole-rat brain derived lipid bilayers exposed to 8 μM of human Aβ for 2 hours. (A) The naked mole-rat brain derived bilayer before Aβ adsorption in PBS exhibiting the high degree of phase separation characteristic of naked mole-rat bilayers. (B, C) Naked mole-rat brain derived bilayer exposed to 8 μM of human Aβ for 2 hours. (D) A height profile corresponding to the blue horizontal line in (C), confirming the height of fragments to be of bilayer thickness of 4 nm.