COVID-19 Research Paper Volume 12, Issue 22 pp 22413—22424

Estimating the release of inflammatory factors and use of glucocorticoid therapy for COVID-19 patients with comorbidities

Figure 4. Variation of chest CT images, inflammatory cytokines, and lymphocyte count in severe COVID-19 patients with and without comorbidities. CT images from a 70-year-old male with diabetes showing bilateral lungs before treatment and infiltrating inflammation after one week of treatment. (B) CT images from a 72-year-old female with diabetes and hypertension showing infiltrating inflammation in bilateral lungs before treatment and deteriorated lung inflammation after one week of treatment. (CE) Serum levels of IL-6 and IFN-γ progressively increased and lymphocytes decreased with disease progression. (FH) Decreased serum levels of IL-6 and IFN-γ, and recovered lymphocytes before and after glucocorticoid treatment (T).