Figure 1. Reduced serum IGF2 protein levels and reduced Igf2 expressions in oocytes from aged mice. (A) Serum IGF2 concentration in young and aged mice assessed via ELISA. n=3 for each group. (B) qPCR results showing mRNA levels of Igf2 and target genes in GV-stage and MII-stage oocytes from young and aged mice. Student’s t-test (two-tailed). *p < 0.05. Error bars indicate the SEM.