Research Paper Volume 13, Issue 2 pp 2379—2396

Dysregulation of FOXD2-AS1 promotes cell proliferation and migration and predicts poor prognosis in oral squamous cell carcinoma: a study based on TCGA data

Expression level of FOXD2-AS1 was upregulated in most cancer types including OSCC. (A) FOXD2-AS1 expression in pan-cancer from normal TCGA samples of GTEx combined with samples of TCGA head and neck squamous cell carcinoma. (B) FOXD2-AS1 expression in pan-cancer of tumor tissues and paracancer tissues from TCGA. (C) FOXD2-AS1 expression of normal samples and tumor samples in TCGA head and neck squamous cell carcinoma. (D) FOXD2-AS1 expression of normal samples and tumor samples in OSCC patients. (E) FOXD2-AS1 expression of tumor tissues and paracancer tissues in OSCC patients. (F) ROC analysis of FOXD2-AS1 expression showing promising discrimination power between tumor and normal tissues.

Figure 1. Expression level of FOXD2-AS1 was upregulated in most cancer types including OSCC. (A) FOXD2-AS1 expression in pan-cancer from normal TCGA samples of GTEx combined with samples of TCGA head and neck squamous cell carcinoma. (B) FOXD2-AS1 expression in pan-cancer of tumor tissues and paracancer tissues from TCGA. (C) FOXD2-AS1 expression of normal samples and tumor samples in TCGA head and neck squamous cell carcinoma. (D) FOXD2-AS1 expression of normal samples and tumor samples in OSCC patients. (E) FOXD2-AS1 expression of tumor tissues and paracancer tissues in OSCC patients. (F) ROC analysis of FOXD2-AS1 expression showing promising discrimination power between tumor and normal tissues.