Research Paper Volume 13, Issue 2 pp 2750—2767

ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum

The expression of GRP78 in Alda1-treated mice during the normal aging process. (A, B) A typical WB image of GRP78 and the confirmation of GRP78 expression by WB; (C, D) A typical immunofluorescence image of GRP78 and the confirmation of GRP78 expression by immunofluorescence. Scale bar: 50 μm. All analyses were performed in duplicate. Values are presented as the mean ± SD, n = 4 mice per group. *Pvs young; #Pvs aged (DMSO).

Figure 9. The expression of GRP78 in Alda1-treated mice during the normal aging process. (A, B) A typical WB image of GRP78 and the confirmation of GRP78 expression by WB; (C, D) A typical immunofluorescence image of GRP78 and the confirmation of GRP78 expression by immunofluorescence. Scale bar: 50 μm. All analyses were performed in duplicate. Values are presented as the mean ± SD, n = 4 mice per group. *P<0.05: aged (DMSO) and aged (Alda1) vs young; #P<0.05: aged (Alda1) vs aged (DMSO).