Figure 4. Changes of cytokine levels and changes of LSEC structure in the in vitro coculture experiments. (A) Analysis of cytokines (IFN-γ and IL-4) levels at different coculture time points. (B) Distribution and size variance of fenestrae in each group after coculture for 3 h (the yellow head of arrow indicates fenestrae on the LSECs). (C) Quantification of fenestrae number and porosity of each group in (B). *p < 0.05, **p < 0.01, ***p < 0.001.