Research Paper Volume 13, Issue 2 pp 3112—3145

Identification of core genes for early diagnosis and the EMT modulation of ovarian serous cancer by bioinformatics perspective

Overall survival impact of key genes on patients with OSC at different stages. (A) Survival prognosis forest map related to key genes at early stages (stages I+II) in OSC patients. Each point in the forest plot represents the Hazard ratio (HR) of the gene, and the lines on both sides of the point represent the 95% confidence interval (95%CI). Survival curves were constructed by the Kaplan-Meier plotter based on the low and high expression of the key genes in OSC patients, including (B) NDC80, (C) MCM2, (D) KAT2B and (E) BUB1B. (F) Survival prognosis forest map related to key genes at advanced stages (stages III+IV) in OSC patients. Kaplan-Meier overall survival analysis for OSC patients with the expression of key genes, covering (G) NDC80, (H) MCM2, (I) KAT2B and (J) BUB1B. Logrank p-value

Figure 5. Overall survival impact of key genes on patients with OSC at different stages. (A) Survival prognosis forest map related to key genes at early stages (stages I+II) in OSC patients. Each point in the forest plot represents the Hazard ratio (HR) of the gene, and the lines on both sides of the point represent the 95% confidence interval (95%CI). Survival curves were constructed by the Kaplan-Meier plotter based on the low and high expression of the key genes in OSC patients, including (B) NDC80, (C) MCM2, (D) KAT2B and (E) BUB1B. (F) Survival prognosis forest map related to key genes at advanced stages (stages III+IV) in OSC patients. Kaplan-Meier overall survival analysis for OSC patients with the expression of key genes, covering (G) NDC80, (H) MCM2, (I) KAT2B and (J) BUB1B. Logrank p-value<0.05 was considered statistically significant.