Research Paper Volume 13, Issue 2 pp 3112—3145

Identification of core genes for early diagnosis and the EMT modulation of ovarian serous cancer by bioinformatics perspective

GRN analysis of core genes and EMT regulators. (A) Network of TFs-core genes and EMT regulators was obtained from ENCODE database. (B) Network of miRNAs-core genes and EMT regulators was obtained from TarBase and miRTarBase database. (C) Integrative regulatory network of TFs-miRNAs-core genes and EMT regulators. (D) Core genes and EMT regulators regulated by TFs. (E) Core genes and EMT regulators modulated by miRNAs.

Figure 7. GRN analysis of core genes and EMT regulators. (A) Network of TFs-core genes and EMT regulators was obtained from ENCODE database. (B) Network of miRNAs-core genes and EMT regulators was obtained from TarBase and miRTarBase database. (C) Integrative regulatory network of TFs-miRNAs-core genes and EMT regulators. (D) Core genes and EMT regulators regulated by TFs. (E) Core genes and EMT regulators modulated by miRNAs.