Research Paper Volume 13, Issue 5 pp 7180—7189

Neuroprotective effect of hydrogen sulfide against glutamate-induced oxidative stress is mediated via the p53/glutaminase 2 pathway after traumatic brain injury

Treatment with H2S inhibited TBI-induced glutamate. (A) The level of glutamate in TBI-challenged rats after treatment with NaHS. (B) Western blot was performed to analyze the protein level of GLS-2 in TBI-challenged rats after treatment with NaHS. (C) The band density of GLS-2 was analyzed using Image J. * P

Figure 3. Treatment with H2S inhibited TBI-induced glutamate. (A) The level of glutamate in TBI-challenged rats after treatment with NaHS. (B) Western blot was performed to analyze the protein level of GLS-2 in TBI-challenged rats after treatment with NaHS. (C) The band density of GLS-2 was analyzed using Image J. * P<0.05, vs. TBI and TBI+ vehicle groups. #P<0.05, ###P<0.001 vs. sham group.