Research Paper Volume 13, Issue 5 pp 7259—7283

Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

Evaluation of the prognostic significance of Fuz mRNA expression in different cancer types. Kaplan-Meier pan-cancer survival analysis was performed to evaluate the relationship between Fuz mRNA level and overall survival probabilities in 21 different types of cancer. Low level of Fuz expression was found associated with poor prognosis in BRCA, ESCA, HNSC, KIRC, KIRP and LUAD patients, whilst high level of Fuz expression was found associated with poor prognosis in LIHC and STAD patients.

Figure 1. Evaluation of the prognostic significance of Fuz mRNA expression in different cancer types. Kaplan-Meier pan-cancer survival analysis was performed to evaluate the relationship between Fuz mRNA level and overall survival probabilities in 21 different types of cancer. Low level of Fuz expression was found associated with poor prognosis in BRCA, ESCA, HNSC, KIRC, KIRP and LUAD patients, whilst high level of Fuz expression was found associated with poor prognosis in LIHC and STAD patients.