Research Paper Volume 13, Issue 5 pp 7382—7396

Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma

Exosomal miR-149-5p promoted lung adenocarcinoma cells proliferation. (A) Upregulation of exosomal miR-149-5p in A549 cells compared to HBE cells. (B) The effect of GW4869 in A549 cells. (C) The expression level of exosomal miR-149-5p in cells and exosomes with the treatment of GW4869. (D) The expression of miR-149-5p in A549 cells with different treatments. (E) The expression of exosomal miR-149-5p in A549 cells with different treatments. (F) The growth abilities of A549 cells with different treatments. (G) The apoptotic rates of A549 cells with different treatments. **pp

Figure 4. Exosomal miR-149-5p promoted lung adenocarcinoma cells proliferation. (A) Upregulation of exosomal miR-149-5p in A549 cells compared to HBE cells. (B) The effect of GW4869 in A549 cells. (C) The expression level of exosomal miR-149-5p in cells and exosomes with the treatment of GW4869. (D) The expression of miR-149-5p in A549 cells with different treatments. (E) The expression of exosomal miR-149-5p in A549 cells with different treatments. (F) The growth abilities of A549 cells with different treatments. (G) The apoptotic rates of A549 cells with different treatments. **p<0.01, ***p<0.001.