Research Paper Volume 13, Issue 5 pp 7538—7548

SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice

The level of m6A RNA modification is elevated in hypoxia-induced PAH, whereas impaired by SMCs specific SETD2 deficient. (A) The content of m6A was quantitatively determined by colorimetry. (B) The content of m6A was qualitatively evaluated by Dot blot. All data were presented as Mean±SD (n=5). *P

Figure 6. The level of m6A RNA modification is elevated in hypoxia-induced PAH, whereas impaired by SMCs specific SETD2 deficient. (A) The content of m6A was quantitatively determined by colorimetry. (B) The content of m6A was qualitatively evaluated by Dot blot. All data were presented as Mean±SD (n=5). *P<0.05 vs. corresponding group.