Research Paper Volume 13, Issue 6 pp 8228—8247

Long non-coding RNAs ENST00000429730.1 and MSTRG.93125.4 are associated with metabolic activity in tuberculosis lesions of sputum-negative tuberculosis patients

Identification and hierarchical clustering analysis of differentially expressed mRNAs and lncRNAs between lung tissue samples with high metabolic activity (PET-high) and lung tissue samples with low metabolic activity (PET-low). (A) scatter plot of mRNAs with |log2 fold change (FC) | > 1; (B) volcano plot of mRNAs with |log2FC | > 1 (FC > 2) and q value C) Hierarchical clustering heatmap of differentially expressed mRNAs; (D) scatter plot of lncRNAs with |log2 FC | > 0.5 (FC > 1.41); (E) volcano plot of lncRNAs with |log2 FC | > 0.5 and q value F) hierarchical clustering heatmap of differentially expressed lncRNAs.

Figure 1. Identification and hierarchical clustering analysis of differentially expressed mRNAs and lncRNAs between lung tissue samples with high metabolic activity (PET-high) and lung tissue samples with low metabolic activity (PET-low). (A) scatter plot of mRNAs with |log2 fold change (FC) | > 1; (B) volcano plot of mRNAs with |log2FC | > 1 (FC > 2) and q value < 0.05; (C) Hierarchical clustering heatmap of differentially expressed mRNAs; (D) scatter plot of lncRNAs with |log2 FC | > 0.5 (FC > 1.41); (E) volcano plot of lncRNAs with |log2 FC | > 0.5 and q value < 0.05; (F) hierarchical clustering heatmap of differentially expressed lncRNAs.