Research Paper Volume 13, Issue 6 pp 8497—8509

Linc00641 promotes the progression of gastric carcinoma by modulating the miR-429/Notch-1 axis

Effects of linc00641 silencing on viability and apoptosis. (A) Linc00641 expression was detected by real-time PCR in gastric cancer cells after linc00641 siRNA transfection. (B) Cell viability was tested by MTT assays. Linc00641 downregulation reduced the viability of the gastric cancer cells. (C) Left panel: Cell apoptosis was detected by flow cytometry in gastric cancer cells 48 hours after linc00641 siRNA transfection. Linc00641 downregulation induced the apoptosis of gastric cancer cells. Right panel: Quantification of the apoptosis results. *P

Figure 1. Effects of linc00641 silencing on viability and apoptosis. (A) Linc00641 expression was detected by real-time PCR in gastric cancer cells after linc00641 siRNA transfection. (B) Cell viability was tested by MTT assays. Linc00641 downregulation reduced the viability of the gastric cancer cells. (C) Left panel: Cell apoptosis was detected by flow cytometry in gastric cancer cells 48 hours after linc00641 siRNA transfection. Linc00641 downregulation induced the apoptosis of gastric cancer cells. Right panel: Quantification of the apoptosis results. *P < 0.05 compared with control siRNA.