Research Paper Volume 13, Issue 6 pp 8563—8587

A novel panel based on immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinoma

Landscape of mutation profiles of 8 followed-up HCC patients with recurrence risk. (A) Mutation information of Top 100 genes in each sample. Different colors and notes at the bottom represented types of mutations. (B) Summary of variant classification, variant type and SNV class information. (C) Time points of the recurrence of P7 and P11, and the location of the lesions. (D) TMB distribution of each patients and somatic mutation in immune-related genes among these HCC patients. TMB, tumor mutational burden; IF, Infiltration.

Figure 2. Landscape of mutation profiles of 8 followed-up HCC patients with recurrence risk. (A) Mutation information of Top 100 genes in each sample. Different colors and notes at the bottom represented types of mutations. (B) Summary of variant classification, variant type and SNV class information. (C) Time points of the recurrence of P7 and P11, and the location of the lesions. (D) TMB distribution of each patients and somatic mutation in immune-related genes among these HCC patients. TMB, tumor mutational burden; IF, Infiltration.