Research Paper Volume 13, Issue 6 pp 8563—8587

A novel panel based on immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinoma

Construction and evaluation of the TMB-IF prognostic panel. (A) Overall distribution of patients identified with the threshold of high and low risk. Screened prognostic genes in the two groups was demonstrated by heatmap. (B) Kaplan–Meier survival analysis and survival curves of high and low risk patients. (C) ROC curve of the prognostic model at 0.5-, 1-, 1.5- and 3-year overall survival. (D) Comparison of TMB-IF with TNM staging and Pathology Grade. ROC, Receiver operating characteristic; TMB, tumor mutational burden; IF, infiltration.

Figure 6. Construction and evaluation of the TMB-IF prognostic panel. (A) Overall distribution of patients identified with the threshold of high and low risk. Screened prognostic genes in the two groups was demonstrated by heatmap. (B) Kaplan–Meier survival analysis and survival curves of high and low risk patients. (C) ROC curve of the prognostic model at 0.5-, 1-, 1.5- and 3-year overall survival. (D) Comparison of TMB-IF with TNM staging and Pathology Grade. ROC, Receiver operating characteristic; TMB, tumor mutational burden; IF, infiltration.