Research Paper Volume 13, Issue 7 pp 9627—9645

Hsa_circ_0053063 inhibits breast cancer cell proliferation via hsa_circ_0053063/hsa-miR-330-3p/PDCD4 axis

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Figure 3. Hsa_circ_0053063 inhibits BC tumor growth in vivo. (A) Hsa_circ_0053063 overexpression efficiency in MDA-MB-231 cells was affirmed by qRT-PCR. (B) The nude mice injected into the fat pad of the right second breast. (C–D) The mice tumors were photographed and measured. (E–F) IHC assay revealed PDCD4 protein expression in the over-expression group and NC group. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).