Research Paper Volume 13, Issue 8 pp 11083—11095

circUBAP2 exacerbates malignant capabilities of NSCLC by targeting KLF4 through miR-3182 modulation

(A) RT-PCR detection of circUBAP2

Figure 3. (A) RT-PCR detection of circUBAP2_046 and UBAP2 expression level in A549 cell line transfected by three different circUBAP2_046 specific shRNAs. (B) RT-PCR detection of circUBAP2_046 and UBAP2 expression level in NCI-H1299 cell line transfected with circUBAP2_046 over-expression vector. (CE) Measurement of cell survival rate of cell groups (A549 cell group silenced by sh-circUBAP2_046, NCI-H1299 over-expressed by circUBAP2_046 and control group) treated with Docetaxel/Doxorubicin/Gefitinib of different concentrations.