Research Paper Volume 13, Issue 6 pp 9011—9027

Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing

Functional enrichment analysis of DEGs from RNA-seq data. (A) The plot showed the top 20 significantly enriched KEGG pathways of differentially expressed genes (DEGs) associated with Pias1 regulation with an FDR value cutoff of 0.05. Round size represents the gene count of each pathway, and the color represents the significance level. (B) The bar chart showed the categories of significantly enriched pathways. There were five pathway categories including cellular processes (red), environmental information processing (green yellow), human diseases (green), metabolism (blue) and organismal systems (purple).

Figure 5. Functional enrichment analysis of DEGs from RNA-seq data. (A) The plot showed the top 20 significantly enriched KEGG pathways of differentially expressed genes (DEGs) associated with Pias1 regulation with an FDR value cutoff of 0.05. Round size represents the gene count of each pathway, and the color represents the significance level. (B) The bar chart showed the categories of significantly enriched pathways. There were five pathway categories including cellular processes (red), environmental information processing (green yellow), human diseases (green), metabolism (blue) and organismal systems (purple).