Research Paper Volume 13, Issue 7 pp 10603—10618

Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma

DCAF15 and ZEB1 protein levels negatively correlate in HCC patient specimens. (A–B) In random 7 HCC patient specimens. protein level of DCAF15 in tumor tissues is lower than in normal tissues. (C) Representative western blotting figures show protein expression of DCAF15 and ZEB1 in 40 HCC patient specimens. (D) Correlation analysis of the expression levels of DCAF15 and ZEB1 protein in 40 HCC patient specimens (r = −0.46, p = 0.006).

Figure 7. DCAF15 and ZEB1 protein levels negatively correlate in HCC patient specimens. (AB) In random 7 HCC patient specimens. protein level of DCAF15 in tumor tissues is lower than in normal tissues. (C) Representative western blotting figures show protein expression of DCAF15 and ZEB1 in 40 HCC patient specimens. (D) Correlation analysis of the expression levels of DCAF15 and ZEB1 protein in 40 HCC patient specimens (r = −0.46, p = 0.006).