Research Paper Volume 13, Issue 7 pp 10603—10618

Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma

A mechanism of DCAF15 function as a tumor suppressor through ubiquitination and degradation of ZEB1 leads to proliferation, invasion and EMT of HCC.

Figure 8. A mechanism of DCAF15 function as a tumor suppressor through ubiquitination and degradation of ZEB1 leads to proliferation, invasion and EMT of HCC.