Research Paper Volume 13, Issue 7 pp 10659—10671

Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway

(A) Effect of fisetin on blood glucose in STZ+Vehicle and STZ+Resveratrol mice. (B) Mechanical nociceptive thresholds: ordinates represent the filament weight (0.1g) in which the animal responds in of presentations. (C) Thermal nociceptive threshold: the axis of ordinates represents the time (seconds) the animal takes to withdraw its paw. (Control group represents mice without administered with streptozotocin. 2 weeks after induction, mice were treated with Resveratrol or Vehicle (DMSO), n = 10 mice for each group, data are represented as the mean ± SEM.)

Figure 1. (A) Effect of fisetin on blood glucose in STZ+Vehicle and STZ+Resveratrol mice. (B) Mechanical nociceptive thresholds: ordinates represent the filament weight (0.1g) in which the animal responds in of presentations. (C) Thermal nociceptive threshold: the axis of ordinates represents the time (seconds) the animal takes to withdraw its paw. (Control group represents mice without administered with streptozotocin. 2 weeks after induction, mice were treated with Resveratrol or Vehicle (DMSO), n = 10 mice for each group, data are represented as the mean ± SEM.)