Research Paper Volume 13, Issue 8 pp 11833—11859

Transcriptome integration analysis and specific diagnosis model construction for Hodgkin's lymphoma, diffuse large B-cell lymphoma, and mantle cell lymphoma

Evaluation of single-gene models in three types of lymphoma. (A–C) The classification performance of HL marker genes, DLBCL marker genes, and MCL marker genes using a univariate logistic regression model. The diamond shape indicates the odds ratio (OR), and the line indicates the 95% confidence interval (CI). The red color indicates OR > 1, and the blue color indicates OR D) The area under the curve (AUC) of the marker genes in three types of lymphoma. (E–G) Receiver operating characteristic (ROC) curves of the optimal single-gene model in HL (MYH2), DLBCL (LIPF), and MCL (IGLV3-19). HL, Hodgkin's lymphoma; DLBCL, diffuse large B-cell lymphoma; MCL, mantle cell lymphoma.

Figure 3. Evaluation of single-gene models in three types of lymphoma. (AC) The classification performance of HL marker genes, DLBCL marker genes, and MCL marker genes using a univariate logistic regression model. The diamond shape indicates the odds ratio (OR), and the line indicates the 95% confidence interval (CI). The red color indicates OR > 1, and the blue color indicates OR < 1. (D) The area under the curve (AUC) of the marker genes in three types of lymphoma. (EG) Receiver operating characteristic (ROC) curves of the optimal single-gene model in HL (MYH2), DLBCL (LIPF), and MCL (IGLV3-19). HL, Hodgkin's lymphoma; DLBCL, diffuse large B-cell lymphoma; MCL, mantle cell lymphoma.