Research Paper Volume 13, Issue 8 pp 11954—11968

Influence of atorvastatin on metabolic pattern of rats with pulmonary hypertension

PLS-DA analysis was used to investigate the influence of Ato on the metabonomics of PAH rats. (A) The serum metabolic patterns of rats in different groups can be distinguished; (B) The metabonomics differences between group control and Ato (1 week) could be distinguished; (C) The metabonomics differences between group Ato (1 week) and Ato (2-3 week) could be distinguished; (D) The metabonomics differences between group Ato (2-3 week) and Ato (4 week) could be distinguished.

Figure 2. PLS-DA analysis was used to investigate the influence of Ato on the metabonomics of PAH rats. (A) The serum metabolic patterns of rats in different groups can be distinguished; (B) The metabonomics differences between group control and Ato (1 week) could be distinguished; (C) The metabonomics differences between group Ato (1 week) and Ato (2-3 week) could be distinguished; (D) The metabonomics differences between group Ato (2-3 week) and Ato (4 week) could be distinguished.