Research Paper Volume 13, Issue 10 pp 14159—14169

Silencing lncRNA AK136714 reduces endothelial cell damage and inhibits atherosclerosis

AK136714 is reduced in plaque tissue and blood of atherosclerotic mice. (A) GEO database analysis identified dysregulated lncRNAs in plaques from a mouse atherosclerosis model. (B) Volcano map showing the gene distribution. (C) Detection of AK136714 expression in plaques of atherosclerotic mice using qPCR. (D) Detection of AK136714 expression in the blood of atherosclerotic mice using qPCR. (n=8, *P

Figure 1. AK136714 is reduced in plaque tissue and blood of atherosclerotic mice. (A) GEO database analysis identified dysregulated lncRNAs in plaques from a mouse atherosclerosis model. (B) Volcano map showing the gene distribution. (C) Detection of AK136714 expression in plaques of atherosclerotic mice using qPCR. (D) Detection of AK136714 expression in the blood of atherosclerotic mice using qPCR. (n=8, *P < 0.05).